ARG83639
Human Apolipoprotein H ELISA Kit
Human Apolipoprotein H ELISA 试剂盒 for ELISA and Human
概述
| 产品描述 | ARG83639 Human Apolipoprotein H ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Apolipoprotein H in serum, plasma and urine |
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| 反应物种 | Hu |
| 应用 | ELISA |
| 靶点名称 | Apolipoprotein H |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 3.0 ng/ml |
| 样品类型 | Serum, plasma and urine |
| 标准范围 | 3.125 - 200 ng/ml |
| 样本量 | 100 μl |
| 精确 | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
| 別名 | APOH; Apolipoprotein H; B2G1; BG; Apolipoprotein H (Beta-2-Glycoprotein I); Activated Protein C-Binding Protein; Anticardiolipin Cofactor ; Beta-2-Glycoprotein I; Beta-2-Glycoprotein 1; APC Inhibitor; Beta(2)GPI; B2GPI; Apo-H; Epididymis Secretory Sperm Binding Protein; B2GP1 |
应用说明
| 检测时间 | 2.5 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 4°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | APOH |
| 全名 | Apolipoprotein H |
| 背景介绍 | Apolipoprotein H, also known as beta-2-glycoprotein I, is a component of circulating plasma lipoproteins. It has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, hemostasis, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome (APS). The anti-beta (2) glycoprotein I antibodies from APS patients, mediate inhibition of activated protein C which has anticoagulant properties. Because beta-2-GPI is the main autoantigen in patients with APS, the disruption of this pathway by autoantibodies may be an important mechanism for thrombosis in patients with APS.[provided by RefSeq, Dec 2019] |
| 生物功能 | Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. [UniProt] |
| Title | Download Link |
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| Human Apolipoprotein H ELISA Kit User manual |
 Download
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