ARG81331
Human CD261 / TRAIL-R1 ELISA Kit
Human CD261 / TRAIL-R1 ELISA 试剂盒 for ELISA and Human
概述
| 产品描述 | ARG81331 Human CD261 / TRAIL-R1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CD261 / TRAIL-R1 in serum, plasma and cell culture supernatant. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | Specific for Human CD261 / TRAIL-R1. No cross reactivity observed with TRAIL, CD117, IL-6R, IL-2R, CD116, TRAIL R2, TRAIL R3, TRAIL R4, CD178 and Granzyme B. |
| 靶点名称 | CD261 / TRAIL R1 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 8 pg/ml |
| 样品类型 | Serum, plasma and cell culture supernatants. |
| 标准范围 | 31.25 - 1000 pg/ml |
| 样本量 | 100 µl |
| 別名 | TNF-related apoptosis-inducing ligand receptor 1; CD antigen CD261; TRAILR-1; DR4; Tumor necrosis factor receptor superfamily member 10A; CD261; Death receptor 4; APO2; TRAIL receptor 1; TRAIL-R1; TRAILR1 |
应用说明
| 检测时间 | ~ 2.5 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O00220 Human Tumor necrosis factor receptor superfamily member 10A |
|---|---|
| 基因名称 | TNFRSF10A |
| 全名 | tumor necrosis factor receptor superfamily, member 10a |
| 背景介绍 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008] |
| 生物功能 | Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. [UniProt] |
| 产品亮点 | Related products: CD261 antibodies; CD261 ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
检测图片 (1) Click the Picture to Zoom In
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ARG81331 Human CD261 / TRAIL-R1 ELISA Kit standard curve image
ARG81331 Human CD261 / TRAIL-R1 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG81331 Human CD261 / TRAIL-R1 ELISA Kit User's manual |
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