ARG70511
Human CD66c recombinant protein (His-tagged)
Human CD66c recombinant protein (His-tagged) for SDS-PAGE
概述
| 产品描述 | CHO expressed, His-tagged Human CD66c recombinant protein. |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | CD66c |
| 物种 | Human |
| A.A. 序列 | Met1 - Gly320 |
| 表达系统 | CHO |
| Protein Full name | Carcinoembryonic antigen-related cell adhesion molecule 6 |
| 別名 | CEACAM6; CEA Cell Adhesion Molecule 6; CD66c; NCA; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (Non-Specific Cross Reacting Antigen); Carcinoembryonic Antigen Related Cell Adhesion Molecule 6; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6; Normal Cross-Reacting Antigen; NCA-50/90; Non-Specific Crossreacting Antigen; Cluster Of Differentiation 66c; CD66c Antigen; CEAL |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in 4 mM HCl to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | CEACAM6 |
|---|---|
| 全名 | CEA Cell Adhesion Molecule 6 |
| 背景介绍 | This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq, Apr 2014] |
| 生物功能 | Also involved in the metastatic cascade process by inducing gain resistance to anoikis of pancreatic adenocarcinoma and colorectal carcinoma cell. [UniProt] |
