ARG81327
Human CD86 ELISA Kit
Human CD86 ELISA 试剂盒 for ELISA and Human
概述
| 产品描述 | ARG81327 Human CD86 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CD86 in serum, plasma and cell culture supernatant. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | Recognizes natural Human soluble CD86. No cross reactivity with other Human soluble molecules. |
| 靶点名称 | CD86 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 0.6 U/ml |
| 样品类型 | Serum, plasma and cell culture supernatants. |
| 标准范围 | 1.1875 - 38 U/ml |
| 样本量 | 100 µl |
| 別名 | B70; B7.2; LAB72; CD antigen CD86; B7-2; FUN-1; CD28LG2; T-lymphocyte activation antigen CD86; CTLA-4 counter-receptor B7.2; Activation B7-2 antigen; BU63 |
应用说明
| 检测时间 | ~ 3 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P42081 Human T-lymphocyte activation antigen CD86 |
|---|---|
| 基因名称 | CD86 |
| 全名 | CD86 molecule |
| 背景介绍 | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011] |
| 生物功能 | Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. [UniProt] |
| 产品亮点 | Related products: CD86 antibodies; CD86 ELISA Kits; Related news: New PD-1 ELISA Kit, excellent for preclinical studies or pharmatheutical development New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 翻译后修饰 | Polyubiquitinated; which is promoted by MARCH8 and results in endocytosis and lysosomal degradation. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG81327 Human CD86 ELISA Kit standard curve image
ARG81327 Human CD86 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG81327 Human CD86 ELISA Kit User's manual |
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