ARG70431
Human CXCL13 / BCA1 recombinant protein (Active) (His-tagged, N-ter)
Human CXCL13 / BCA1 recombinant protein (Active) (His-tagged, N-ter) for SDS-PAGE
概述
| 产品描述 | E. coli expressed, His-tagged (N-ter) Active Human CXCL13 / BCA1 recombinant protein |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | CXCL13 / BCA1 |
| 物种 | Human |
| A.A. 序列 | Val23 - Arg94 |
| 表达系统 | E. coli |
| Protein Full name | C-X-C motif chemokine 13 |
| 生物活性 | Active |
| 活性说明 | Determined by its ability to chemoattract BaF3 cells transfected with human CXCR5. The ED50 for this effect is < 20 ng/mL. |
| 別名 | CXCL13; C-X-C Motif Chemokine Ligand 13; BCA-1; BLC; ANGIE2; SCYB13; BLR1L; ANGIE; Small Inducible Cytokine B Subfamily (Cys-X-Cys Motif), Member 13 (B-Cell Chemoattractant); B Cell-Attracting Chemokine; B Lymphocyte Chemoattractant |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | > 98% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | CXCL13 |
|---|---|
| 全名 | C-X-C Motif Chemokine Ligand 13 |
| 背景介绍 | B lymphocyte chemoattractant, independently cloned and named Angie, is an antimicrobial peptide and CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles. |
| 生物功能 | Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B-lymphocytes. Binds to BLR1/CXCR5. |
| 细胞定位 | Secreted |
| 翻译后修饰 | Disulfide bond |
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ARG70431 Human CXCL13 / BCA1 recombinant protein (Active) (His-tagged, N-ter)SDS-PAGE image
SDS-PAGE analysis of ARG70431 Human CXCL13 / BCA1 recombinant protein (Active) (His-tagged, N-ter)
