ARG70473
Human IL18 recombinant protein (Active) (Tag free)
Human IL18 recombinant protein (Active) (Tag free) for SDS-PAGE
概述
| 产品描述 | E. coli expressed, Active Human IL18 recombinant protein |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | IL18 |
| 物种 | Human |
| A.A. 序列 | Tyr37 - Asp193 |
| 表达系统 | E. coli |
| 生物活性 | Active |
| 活性说明 | Determined by its ability to induce IFN gamma secretion in KG-1 cells. The ED50 for this effect is < 6 ng/mL. |
| 別名 | Iboctadekin; Interferon gamma-inducing factor; Interleukin-18; IL-18; IFN-gamma-inducing factor; IL-1 gamma; IGIF; IL-1g; Interleukin-1 gamma; IL1F4 |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | IL18 |
|---|---|
| 全名 | interleukin 18 |
| 背景介绍 | The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011] |
| 生物功能 | Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 翻译后修饰 | The pro-IL-18 precursor is processed by CASP1 or CASP4 to yield the active form. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG70473 Human IL18 recombinant protein (Active) (Tag free) SDS-PAGE image
SDS-PAGE analysis of Human IL18 recombinant protein (Active) (Tag free)
