ARG82058
Human PDGF DD ELISA Kit
Human PDGF DD ELISA 试剂盒 for ELISA and Human
概述
| 产品描述 | Human PDGF DD ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human PDGF DD in serum, plasma and cell culture supernatants. |
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| 反应物种 | Hu |
| 应用 | ELISA |
| 靶点名称 | PDGF DD |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 7.8 pg/ml |
| 样品类型 | Serum, plasma and cell culture supernatants. |
| 标准范围 | 15.6 - 1000 pg/ml |
| 样本量 | 100 µl |
| 別名 | SCDGFB; Iris-expressed growth factor; PDGFD receptor-binding form; PDGFD latent form; MSTP036; Spinal cord-derived growth factor B; IEGF; PDGF-D; SCDGF-B; Platelet-derived growth factor D |
应用说明
| 检测时间 | 4.5 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PDGFD |
| 全名 | platelet derived growth factor D |
| 背景介绍 | The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix (By similarity). [UniProt] |
| 细胞定位 | Secreted. Note=Released by platelets upon wounding. [UniProt] |
| 产品亮点 | Related products: PDGF antibodies; PDGF ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 翻译后修饰 | Activated by proteolytic cleavage. Proteolytic removal of the N-terminal CUB domain releasing the core domain is necessary for unmasking the receptor-binding epitopes of the core domain. Cleavage after Arg-247 or Arg-249 by urokinase plasminogen activator gives rise to the active form. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG82058 Human PDGF DD ELISA Kit standard curve image
ARG82058 Human PDGF DD ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG82058 Human PDGF DD ELISA Kit User manual |
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