ARG83636
Human Tau phospho (Thr231) ELISA Kit
Human Tau phospho (Thr231) ELISA 试剂盒 for ELISA and Human
Neuroscience antibody; Signaling Transduction antibody; Neuron Development Study antibody
概述
| 产品描述 | ARG83636 Human Tau phospho (Thr231) ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Tau phospho (Thr231) in CSF, serum and plasma. |
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| 反应物种 | Hu |
| 应用 | ELISA |
| 靶点名称 | Tau |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 7.8 pg/ml |
| 样品类型 | CSF, serum and plasma. |
| 标准范围 | 15.625 - 1000 pg/ml |
| 样本量 | 50 µl |
| 精确 | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
| 別名 | TAU; Neurofibrillary tangle protein; Paired helical filament-tau; PPND; DDPAC; FTDP-17; MTBT2; Microtubule-associated protein tau; PHF-tau; MSTD; PPP1R103; MTBT1; MAPTL |
应用说明
| 检测时间 | 4 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 4°C, -20°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P10636 Human Microtubule-associated protein tau |
|---|---|
| 基因名称 | MAPT |
| 全名 | microtubule-associated protein tau |
| 背景介绍 | This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008] |
| 生物功能 | Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. [UniProt] |
| 产品亮点 | Related products: Tau antibodies; Tau ELISA Kits; Tau Duos / Panels; Anti-Rabbit IgG secondary antibodies; Related news: "Pro-aging factor" tied to immune-related molecule |
| 研究领域 | Neuroscience antibody; Signaling Transduction antibody; Neuron Development Study antibody |
检测图片 (1) Click the Picture to Zoom In
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ARG83636 Human Tau phospho (Thr231) ELISA Kit standard curve image
ARG83636 Human Tau phospho (Thr231) ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG83636 Human Tau phospho (Thr231) ELISA Kit User manual |
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