ARG82770
MPO / Myeloperoxidase Activity Assay Kit (Colorimetric)
MPO / Myeloperoxidase Activity Assay 试剂盒 (Colorimetric) for Functional study and Human,Mouse,Rat,All
参考文献2
概述
| 产品描述 | ARG82770 MPO / Myeloperoxidase Activity Assay Kit (Colorimetric) can be used to measure Myeloperoxidase activity in whole neutrophils, neutrophil lysates, tissue homogenates and plasma (EDTA). |
|---|---|
| 反应物种 | Hu, Ms, Rat, All |
| 应用 | FuncSt |
| 靶点名称 | MPO / Myeloperoxidase |
| 偶联标记说明 | Read at 405 nm (colorimetric) |
| 灵敏度 | 4.2 µM (0.63 nmol/well, based on 150 µl volume/well) |
| 检测范围 | 4.2 - 333 µM (0.63 - 50 nmol/well, based on 150 µl volume/well) |
| 样品类型 | Whole neutrophils, neutrophil lysates, tissue homogenates and plasma (EDTA). |
| 样本量 | 25 µl |
| 別名 | MPO; Myeloperoxidase; EC 1.11.2.2 |
应用说明
| 应用说明 | Please note that this kit does not include a microplate. |
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| 检测时间 | ~ 2.5 hours |
属性
| 形式 | Liquid |
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| 存放说明 | Store the kit at 2-8°C. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MPO |
| 全名 | myeloperoxidase |
| 背景介绍 | Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014] |
| 生物功能 | Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. [UniProt] |
| 细胞定位 | Lysosome. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG82770 MPO / Myeloperoxidase Activity Assay Kit (Colorimetric) typical data demonstration image
ARG82770 MPO / Myeloperoxidase Activity Assay Kit (Colorimetric) results of a typical standard run with optical density reading at 405 nm, using colorimetric reading.
文献引用
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Hypochlorous Acid Chemistry in Mammalian Cells-Influence on Infection and Role in Various Pathologies
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| Title | Download Link |
|---|---|
| ARG82770 MPO / Myeloperoxidase Activity Assay Kit (Colorimetric) User's manual |
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