ARG30106

Mitochondria / Caspase Dependant Apoptosis Marker Antibody Duo (Caspase9, Cytochrome c)

Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody; Metabolism antibody; Signaling Transduction antibody
publication_link 参考文献2

内含物

货号 内含物名称 宿主克隆性 反应 应用 包装
ARG20048 anti-Caspase 9 (cleaved) antibody Rabbit pAb Hu IP, WB 25 μg
ARG20006 anti-Cytochrome C antibody Rabbit pAb Hu, Ms, Rat, Bov, Chk, Dog IP, WB 25 μg

概述

产品描述 Cytochrome C is an electron transport protein localized in the mitochondria. When a cell receive intra- or extra-cellular death signal, Cytochrome C is then released from mitochondria to cytoplasm and trigger Procaspase 9 activation. Detection of the cytoplasmic release of Cytochrome C and activation of Caspase 9 with anti-Cytochrome C (ARG20006) and anti-Caspase 9 (ARG51317) antibodies are early indications that a cell is undergoing apoptosis.
靶点名称 Mitochondria / Caspase Dependant Apoptosis Marker
別名 Mitochondria/Caspase Dependant Apoptosis Marker antibody; Cytochrome C antibody; Caspase 9 (cleaved) antibody

属性

存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

全名 Antibody Duo for Mitochondria/Caspase Dependant Apoptosis Marker (Caspase9, Cytochrome c)
产品亮点 Related Product:
anti-Cytochrome C antibody;
anti-Dopamine Transporter antibody;
研究领域 Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody; Metabolism antibody; Signaling Transduction antibody

检测图片 (4) Click the Picture to Zoom In

  • ARG20006 anti-Cytochrome C antibody WB image

    Western blot: 20 µg of Mouse testis lysate stained with ARG20006 anti-Cytochrome C antibody at 2 µg/ml dilution.

  • ARG20048 anti-Caspase 9 (cleaved) antibody WB image

    Western blot: 20 µg of HeLa untreated or treated with Staurosporine and stained with ARG20048 anti-Caspase 9 (cleaved) antibody at 1:500 dilution.

  • ARG20006 anti-Cytochrome c antibody WB image

    Western Blot: 1. Jurkat cell lysate 2. 3T3 cell lysate stained with anti-Cytochrome c antibody (ARG20006).

    The cytochrome c antibody detects the 12.6 kDa cytochrome c from human, mouse, and rat samples. Jurkat cell lysate, NIH3T3 cell lysate, and rat kidney tissue lysate can be used as positive controls.

  • ARG20048 anti-Caspase-9 (Active) antibody WB image

    Western Blot: 1. Untreated Jurkat cell lysate 2. Etoposide treated Jurkat cell lysate stained with anti-Caspase 9 active antibody (ARG20048).

    The anti-active caspase-9 antibody recognizes only the cleaved caspase-9 (37 kDa). It does not recognize full-le ngth caspase-9 or any other caspases.

文献引用

Single-Cell Analysis of Signaling Proteins Provides Insights into Proapoptotic Properties of Anticancer Drugs.

ARG20006: scPISA / Human

Yanrong Wen et al.
Anal Chem.,  (2020)

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Probing apoptosis signaling proteins in single living cells for precision efficacy evaluation of anti-cancer drugs.

ARG20006: / Human

Wen Yanrong et al.
Preprint.,  (2019)

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