ARG70489
Mouse CD16 recombinant protein (His-tagged)
Mouse CD16 recombinant protein (His-tagged) for SDS-PAGE
概述
| 产品描述 | CHO expressed, His-tagged Mouse CD16 recombinant protein. |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | CD16 |
| 物种 | Mouse |
| A.A. 序列 | Met1 - Thr215 |
| 表达系统 | CHO |
| Protein Full name | Fc gamma receptor III |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | Fcgr3 |
|---|---|
| 全名 | Fc gamma receptor III |
| 背景介绍 | CD16, also known as Fc gamma receptor III (FcγRIII), is a transmembrane protein primarily found on the surface of natural killer (NK) cells, macrophages, and a subset of T cells. It plays a critical role in mediating antibody-dependent cellular cytotoxicity (ADCC) and phagocytosis. CD16 binds to the Fc portion of immunoglobulin G (IgG) antibodies, facilitating the recognition and destruction of target cells or pathogens coated with antibodies. This interaction activates downstream signaling pathways, triggering cytotoxic responses. CD16's involvement in immune surveillance and host defense highlights its significance in immune regulation and therapeutic strategies targeting ADCC. |
