ARG70401
Mouse CD178 / Fas Ligand recombinant protein (Active) (His-tagged, N-ter)
Mouse CD178 / Fas Ligand recombinant protein (Active) (His-tagged, N-ter) for SDS-PAGE
概述
| 产品描述 | E. coli expressed, His-tagged (N-ter) Active Mouse CD178 / Fas Ligand recombinant protein |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | CD178 / Fas Ligand |
| 物种 | Mouse |
| A.A. 序列 | Gln128 - Leu279 |
| 表达系统 | E. coli |
| Protein Full name | Tumor necrosis factor ligand superfamily member 6 |
| 生物活性 | Active |
| 活性说明 | Determined by its ability to induce apoptosis in Jurkat cells. The ED50 for this effect is < 1 μg /mL. |
| 別名 | FASLG; Fas Ligand; APT1LG1; TNFSF6; CD178; FasL; Tumor Necrosis Factor Ligand Superfamily Member 6; Fas Ligand (TNF Superfamily, Member 6); Apoptosis Antigen Ligand; Fas Antigen Ligand; CD95 Ligand; CD95-L; CD95L; APTL; FASL; Tumor Necrosis Factor (Ligand) Superfamily, Member 6; Mutant Tumor Necrosis Factor Family Member 6; Apoptosis (APO-1) Antigen Ligand 1; Tumor Necrosis Factor Ligand 1A; CD178 Antigen; ALPS1B; TNLG1A |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | > 98% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 8.0) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | FASLG |
|---|---|
| 全名 | Fas Ligand |
| 背景介绍 | This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. |
| 生物功能 | Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. |
| 细胞定位 | Cell membrane, Cytoplasmic vesicle, Lysosome, Membrane, Nucleus, Secreted |
| 翻译后修饰 | Disulfide bond, Glycoprotein, Ubl conjugation |
检测图片 (1) Click the Picture to Zoom In
-
ARG70401 Mouse CD178 / Fas Ligand recombinant protein (Active) (His-tagged, N-ter) SDS-PAGE image
SDS-PAGE analysis of Mouse CD178 / Fas Ligand recombinant protein (Active) (His-tagged, N-ter)
