ARG70502
Mouse CD54 / ICAM1 recombinant protein (His-tagged)
Mouse CD54 / ICAM1 recombinant protein (His-tagged) for SDS-PAGE
概述
产品描述 | CHO expressed, His-tagged Mouse CD54 / ICAM1 recombinant protein. |
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应用 | SDS-PAGE |
靶点名称 | CD54 / ICAM1 |
物种 | Mouse |
A.A. 序列 | Met1 - Asn485 |
表达系统 | CHO |
Protein Full name | Intercellular adhesion molecule 1 |
別名 | ICAM1; Intercellular Adhesion Molecule 1; CD54; BB2; Major Group Rhinovirus Receptor; ICAM-1; Intercellular Adhesion Molecule 1 (CD54), Human Rhinovirus Receptor; Epididymis Secretory Sperm Binding Protein; Cell Surface Glycoprotein P3.58; Human Rhinovirus Receptor; CD54 Antigen; P3.58 |
属性
形式 | Powder |
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纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
纯度 | > 95% (by SDS-PAGE) |
缓冲液 | PBS (pH 7.4) |
复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
基因名称 | ICAM1 |
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全名 | Intercellular Adhesion Molecule 1 |
背景介绍 | his gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008] |
生物功能 | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. [Uniprot] |