ARG70442
Mouse CXCL10 / IP10 recombinant protein (Active) (His-tagged, N-ter)
Mouse CXCL10 / IP10 recombinant protein (Active) (His-tagged, N-ter) for SDS-PAGE
概述
| 产品描述 | E. coli expressed, His-tagged (N-ter) Active Mouse CXCL10 / IP10 recombinant protein |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | CXCL10 / IP10 |
| 物种 | Mouse |
| A.A. 序列 | Pro23 - Pro98 |
| 表达系统 | E. coli |
| Protein Full name | C-X-C motif chemokine 10 |
| 生物活性 | Active |
| 活性说明 | Determined by its ability to chemoattract BaF3 cells transfected with human CXCR3. The ED50 for this effect is < 0.2 μg/mL. |
| 別名 | CXCL10; C-X-C Motif Chemokine Ligand 10; IP-10; GIP-10; SCYB10; IFI10 ; Crg-2; Mob-1; INP10; C7 |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | > 98% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | CXCL10 |
|---|---|
| 全名 | C-X-C Motif Chemokine Ligand 10 |
| 背景介绍 | This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. This gene may also be a key regulator of the 'cytokine storm' immune response to SARS-CoV-2 infection. |
| 生物功能 | Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects. |
| 细胞定位 | Secreted |
| 翻译后修饰 | Citrullination, Disulfide bond |
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ARG70442 Mouse CXCL10 / IP10 recombinant protein (Active) (His-tagged, N-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70442 Mouse CXCL10 / IP10 recombinant protein (Active) (His-tagged, N-ter)
