ARG82066

Mouse DBP / Vitamin D binding protein ELISA Kit

Mouse DBP / Vitamin D binding protein ELISA 试剂盒 for ELISA and Mouse

概述

产品描述 Mouse DBP / Vitamin D binding protein ELISA Kit is an Enzyme Immunoassay kit for the quantification of Mouse DBP / Vitamin D binding protein in serum, plasma and cell culture supernatants.
反应物种 Ms
应用 ELISA
靶点名称 DBP / Vitamin D binding protein
偶联标记 HRP
偶联标记说明 Substrate: TMB and read at 450 nm.
灵敏度 0.15 ng/ml
样品类型 Serum, plasma and cell culture supernatants.
标准范围 0.312 - 20 ng/ml
样本量 100 µl
別名 GRD3; DBP/GC; HEL-S-51; VDBG; VDB; Gc-globulin; DBP; VDBP; Vitamin D-binding protein; Group-specific component

应用说明

检测时间 4.5 hours

属性

形式 96 well
存放说明 Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 14473 Mouse GC

Swiss-port # P21614 Mouse Vitamin D-binding protein

基因名称 GC
全名 group-specific component (vitamin D binding protein)
背景介绍 The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
生物功能 Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes. [UniProt]
细胞定位 Secreted. [UniProt]
产品亮点 Related products:
DBP antibodies; DBP ELISA Kits;
New ELISA data calculation tool:
Simplify the ELISA analysis by GainData
翻译后修饰 Allele GC*1S is O-glycosylated at Thr-436 (PubMed:20079467). The trisaccharide sugar moiety can be modified by the successive removal of neuraminic acid and galactose leaving an O-linked N-acetyl-galactosamine. This conversion is thought to produce a macrophage-activating factor (Gc-MAF). Only a minor proportion of plasma GC is O-glycosylated (PubMed:17360250). The potential N-glycosylation site predicted at Asn-288 is thought to be nonglycosylated. [UniProt]

检测图片 (1) Click the Picture to Zoom In

  • ARG82066 Mouse DBP / Vitamin D binding protein ELISA Kit standard curve image

    ARG82066 Mouse DBP / Vitamin D binding protein ELISA Kit results of a typical standard run with optical density reading at 450 nm.

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