ARG70226
Mouse IFN beta 1a recombinant protein (Active) (His-tagged, C-ter)
Mouse IFN beta 1a recombinant protein (Active) (His-tagged, C-ter) for SDS-PAGE
概述
| 产品描述 | E. coli expressed, His-tagged (C-ter) Active Mouse IFN beta 1a recombinant protein |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | IFN beta 1a |
| 物种 | Mouse |
| A.A. 序列 | Ile22 - Asn182 |
| 表达系统 | E. coli |
| 生物活性 | Active |
| 活性说明 | Determined by its ability to protect HeLa cells infected with encephalomyocarditis (EMC) virus. The ED50 for this effect is < 5 pg/mL. The specific activity of recombinant mouse IFN beta 1a is > 1 x 10^9 IU/mg. |
| 別名 | Fibroblast interferon; IFN-beta; IFNB; IFF; IFB; Interferon beta |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | > 98% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | IFNB1 |
|---|---|
| 全名 | interferon, beta 1, fibroblast |
| 背景介绍 | This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection. [provided by RefSeq, Sep 2015] |
| 生物功能 | Has antiviral, antibacterial and anticancer activities. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 产品亮点 | Related products: IFN beta antibodies; IFN beta ELISA Kits; IFN beta recombinant proteins; Related news: circNDUFB2, a circular RNA (circRNA), activates anti-tumor immunity |
检测图片 (1) Click the Picture to Zoom In
-
ARG70226 Mouse IFN beta 1a recombinant protein (Active) (His-tagged, C-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70226 Mouse IFN beta 1a recombinant protein (Active) (His-tagged, C-ter).
