ARG53955
Mouse anti-Human Lambda Light Chain antibody [4C2] (PE)
Mouse anti-Human Lambda Light Chain 抗体 [4C2] (PE) for Flow cytometry and Human
Immune System antibody
概述
| 产品描述 | PE-conjugated Mouse Monoclonal antibody [4C2] recognizes Human Lambda Light Chain |
|---|---|
| 反应物种 | Hu |
| 不反应物种 | Goat, Gpig, Hm, Rb, Sheep |
| 应用 | FACS |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 4C2 |
| 同位型 | IgG1 |
| 靶点名称 | Lambda Light Chain |
| 抗原物种 | Human |
| 目标Ig | Human Lambda light chains |
| 偶联标记 | PE |
| 別名 | IGL@; IGLC6 |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化说明 | The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary. |
| 缓冲液 | PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA |
| 抗菌剂 | 15 mM Sodium azide |
| 稳定剂 | 0.2% (w/v) high-grade protease free BSA |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | IGL |
| 全名 | immunoglobulin lambda locus |
| 背景介绍 | Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the complement system. Each immunoglobulin molecule consists of two identical heavy chains and two identical light chains. There are two classes of light chains, kappa and lambda. This region represents the germline organization of the lambda light chain locus. The locus includes V (variable), J (joining), and C (constant) segments. During B cell development, a recombination event at the DNA level joins a single V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase, and by somatic hypermutation, which occurs during B cell maturation in the spleen and lymph nodes. Several V segments and three C segments are known to be incapable of encoding a protein and are considered pseudogenes. The locus also includes several non-immunoglobulin genes, many of which are pseudogenes or are predicted by automated computational analysis or homology to other species. [provided by RefSeq, Jul 2008] |
| 研究领域 | Immune System antibody |
检测图片 (1) Click the Picture to Zoom In
-
ARG53955 Mouse anti-Human Lambda Light Chain antibody [4C2] (PE) FACS image
Flow Cytometry: B lymphocytes (CD19+) stained with ARG53955 Mouse anti-Human Lambda Light Chain antibody [4C2] (PE).
