ARG80222

Mouse sRANK Ligand / TNFSF11 / TRANCE ELISA Kit

Mouse sRANK Ligand / TNFSF11 / TRANCE ELISA 试剂盒 for ELISA and Mouse

Cell Biology and Cellular Response kit; Immune System kit

内含物

货号 内含物名称 包装 温度
ARG80222-001 Antibody-coated microplate 8 X 12 strips 4°C. Unused strips should be sealed tightly in the air-tight pouch.
ARG80222-002 Standard (Lyophilized) 3 X 2 ng/vial 4°C
ARG80222-003 Standard diluent buffer 20 ml 4°C
ARG80222-004 Antibody conjugate concentrate 400 µl 4°C
ARG80222-005 Antibody diluent buffer 16 ml 4°C
ARG80222-006 HRP-Streptavidin concentrate 400 µl 4°C (Protect from light)
ARG80222-007 HRP-Streptavidin diluent buffer 16 ml 4°C
ARG80222-008 20X Wash buffer 50 ml 4°C
ARG80222-009 TMB substrate 12ml 4°C (Protect from light)
ARG80222-010 STOP solution 12ml 4°C
ARG80222-011 Plate sealer 4 strips Room temperature

概述

产品描述 ARG80222 Mouse sRANK Ligand / TNFSF11 / TRANCE ELISA Kit is an Enzyme Immunoassay kit for the quantification of Mouse sRANK Ligand / TNFSF11 / TRANCE in Serum, Plasma, Cell culture supernatants.
反应物种 Ms
应用 ELISA
特异性 No significant cross-reactivity or interference with Mouse C10 MIP-1, JE MIP-1 , KC;human GRO beta, GRO gamma, RANTES
靶点名称 sRANK Ligand / TNFSF11 / TRANCE
偶联标记 HRP
偶联标记说明 Substrate: TMB and read at 450 nm
灵敏度 15 pg/ml
样品类型 Serum, Plasma, Cell culture supernatants
标准范围 31.25 - 2000 pg/ml
样本量 100 µl
精确 CV: less than10%
別名 TRANCE; Osteoprotegerin ligand; CD254; sOdf; Receptor activator of nuclear factor kappa-B ligand; OPTB2; RANKL; OPGL; Tumor necrosis factor ligand superfamily member 11; hRANKL2; TNF-related activation-induced cytokine; Osteoclast differentiation factor; ODF; CD antigen CD254

应用说明

检测时间 4 hours

属性

形式 96 well
存放说明 Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 21943 Mouse TNFSF11

Swiss-port # O35235 Mouse Tumor necrosis factor ligand superfamily member 11

基因名称 Tnfsf11
全名 tumor necrosis factor (ligand) superfamily, member 11
背景介绍 This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced tra
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研究领域 Cell Biology and Cellular Response kit; Immune System kit
翻译后修饰 The soluble form of isoform 1 derives from the membrane form by proteolytic processing (By similarity). The cleavage may be catalyzed by ADAM17.

检测图片 (1) Click the Picture to Zoom In

  • ARG80222 Mouse sRANK Ligand / TNFSF11 / TRANCE ELISA Kit standard curve image

    ARG80222 Mouse sRANK Ligand / TNFSF11 / TRANCE ELISA Kit results of a typical standard run with optical density reading at 450 nm.

Title Download Link
ARG80222 Mouse sRANK Ligand / TNFSF11 / TRANCE ELISA Kit User's manual download icon Download