ARG30214

Phospho STAT5A Antibody Duo (Total, pY694)

Gene Regulation antibody; Signaling Transduction antibody
publication_link 参考文献2

内含物

货号 内含物名称 宿主克隆性 反应 应用 包装
ARG51552 anti-STAT5A phospho (Tyr694) antibody Rabbit pAb Hu, Ms, Rat IHC-P, WB 50 μl
ARG65593 anti-STAT5A antibody Rabbit pAb Hu IHC-P, WB 50 μl

概述

产品描述 STAT5A belongs to STAT family of transcription factors which can be activated by various stimuli such as cytokines and growth factors, including IL-2, GM-CSF, Erythropoietin and Thrombopoietin. The phosphorylation of STAT5A at Tyr694 residue by SRS Kinase upon Erythropoietin stimulation triggers its activation and is responsible for EPO-induced signal transduction. STAT5A phosphorylation can also be induced by Prolactin to increase its DNA binding and transcription ability. Lin and Leonard. 2000. Oncogene 19(21):2566 Okutani et al. 2001. Oncogene 20(45):6643 Gouilleux et al. 1994. EMBO J 13(18):4361-9
靶点名称 STAT5A
別名 Phospho STAT5A antibody; Phospho Signal transducer and activator of transcription 5A antibody; STAT5A phospho (Tyr694) antibody; STAT5A antibody

属性

存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

全名 Phospho Signal transducer and activator of transcription 5A (STAT5A) Antibody Duo (Total, pY694)
产品亮点 Related Product:
anti-STAT5A antibody;
研究领域 Gene Regulation antibody; Signaling Transduction antibody

检测图片 (4) Click the Picture to Zoom In

  • ARG51552 anti-STAT5A phospho (Tyr694) antibody WB image

    Western Blot: extracts from K562 cells untreated or treated with G-CSF stained with anti-STAT5A (phospho Tyr694) antibody ARG51552.

  • ARG51552 anti-STAT5A phospho (Tyr694) antibody IHC-P image

    Immunohistochemistry: paraffin-embedded human breast carcinoma tissue stained with anti-STAT5A (phospho Tyr694) antibody ARG51552 (left) or the same antibody preincubated with blocking peptide (right).

  • ARG65593 anti-STAT5A Antibody IHC-P image

    Immunohistochemistry: paraffin-embedded Human breast carcinoma tissue stained with ARG65593 (STAT5A Antibody) at 1/50 dilution, or the same antibody preincubated with synthetic peptide (right). (Original magnification: ×200)

  • ARG65593 anti-STAT5A Antibody WB image

    Western Blot: ARG65593 STAT5A Antibody at 1/500 dilution with 30 μg of lysates.
    (1) HeLa cell
    (2) K562 cell

    Exposure time: 1 minute.

文献引用

Effects of di (2-ethylhexyl) phthalate and high-fat diet on lipid metabolism in rats by JAK2/STAT5.

ARG51552: WB / Rat

Zhang Yuezhu et al.
Environ Sci Pollut Res Int.,  (2019)

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Mono-2-ethylhexyl phthalate (MEHP) promoted lipid accumulation via JAK2/STAT5 and aggravated oxidative stress in BRL-3A cells.

ARG51552: WB / Rat

Zhang Yuezhu et al.
Ecotoxicol Environ Saf.,  (2019)

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