ARG70419
Pig EGF recombinant protein (His-tagged, C-ter)
Pig EGF recombinant protein (His-tagged, C-ter) for SDS-PAGE
概述
| 产品描述 | E. coli expressed, His-tagged (C-ter) Pig EGF recombinant protein |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | EGF |
| 物种 | Pig |
| A.A. 序列 | Asn970 - Arg1022 |
| 表达系统 | E. coli |
| Protein Full name | Pro-epidermal growth factor |
| 別名 | EGF; Epidermal Growth Factor; Pro-Epidermal Growth Factor; Epidermal Growth Factor (Beta-Urogastrone); Beta-Urogastrone; HOMG4; URG |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 8.0) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | EGF |
|---|---|
| 全名 | Epidermal Growth Factor |
| 背景介绍 | This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016] |
| 生物功能 | EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro |
| 细胞定位 | Membrane |
| 翻译后修饰 | Disulfide bond, Glycoprotein |
检测图片 (1) Click the Picture to Zoom In
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ARG70419 Pig EGF recombinant protein (His-tagged, C-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70419 Pig EGF recombinant protein (His-tagged, C-ter)
