ARG70410
Pig IFN gamma recombinant protein (Active) (His-tagged, C-ter)
Pig IFN gamma recombinant protein (Active) (His-tagged, C-ter) for SDS-PAGE
概述
产品描述 | E. coli expressed, His-tagged (C-ter) Active Pig IFNG recombinant protein |
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应用 | SDS-PAGE |
靶点名称 | IFN gamma |
物种 | Pig |
A.A. 序列 | Gln23 - Lys166 |
表达系统 | E. coli |
Protein Full name | Interferon gamma |
生物活性 | Active |
活性说明 | Determined by its ability to protect PK15 cells infected with encephalomyocarditis (EMC) virus. The ED50 for this effect is < 40 pg/mL. |
別名 | IFNG; Interferon Gamma; Immune Interferon; IFN-Gamma; IMD69; IFG; IFI |
属性
形式 | Powder |
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纯化说明 | Endotoxin level is < 0.01 EU/µg of the protein, as determined by the LAL test. |
纯度 | > 95% (by SDS-PAGE) |
缓冲液 | PBS (pH 7.4) |
复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
基因名称 | IFNG |
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全名 | Interferon Gamma |
背景介绍 | This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. |
生物功能 | Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation. |
细胞定位 | Secreted |
翻译后修饰 | Cleavage on pair of basic residues, Glycoprotein, Pyrrolidone carboxylic acid |
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