ARG82636
Porcine PDGF BB ELISA Kit
Porcine PDGF BB ELISA 试剂盒 for ELISA and Pig
概述
| 产品描述 | ARG82636 Porcine PDGF BB ELISA Kit is an Enzyme Immunoassay kit for the quantification of Porcine PDGF BB in serum, plasma and cell culture supernatants. |
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| 反应物种 | Pig |
| 应用 | ELISA |
| 特异性 | The following recombinant Porcine proteins were tested and exhibited no cross-reactivity or interference: ApoAI, BMP1, BMP2, BMP3, BMP4, HGF, HSP27, IFN gamma, IL1 beta, IL1RA, IL2, IL5, IL6, IL8, IL10, IL12, IL13, IL15, IL17C, IL23, MMP2, MMP9, sIL2R, sIL6R, TGF beta 1, TGF beta 2, TGF beta 3, TLR1, TLR2, TLR3, TNF alpha, TNF RI, TNF RII and VEGF. |
| 靶点名称 | PDGF BB |
| 偶联标记 | HRP |
| 偶联标记说明 | Read at 450 nm. |
| 灵敏度 | 20.3 pg/ml |
| 样品类型 | Serum, plasma and cell culture supernatants. |
| 标准范围 | 40.6 - 2600 pg/ml |
| 样本量 | 100 µl |
| 精确 | Intra-Assay CV: 4% Inter-Assay CV: 9% |
| 別名 | SIS; Becaplermin; Platelet-derived growth factor subunit B; IBGC5; PDGF subunit B; c-sis; SSV; PDGF-2; Proto-oncogene c-Sis; Platelet-derived growth factor beta polypeptide; PDGF2; Platelet-derived growth factor B chain |
应用说明
| 检测时间 | ~ 3 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | PDGFB |
|---|---|
| 全名 | platelet-derived growth factor beta polypeptide |
| 背景介绍 | This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit B, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit A. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with dermatofibrosarcoma protuberans, a rare skin tumor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015] |
| 生物功能 | Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin (PubMed:26599395). Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA. [UniProt] |
| 细胞定位 | Secreted. Note=Released by platelets upon wounding. [UniProt] |
| 产品亮点 | Related products: PDGF BB antibodies; PDGF BB ELISA Kits; Related news: The role of HDGF in tumor angiogenesis New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
检测图片 (1) Click the Picture to Zoom In
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ARG82636 Porcine PDGF BB ELISA Kit standard curve image
ARG82636 Porcine PDGF BB ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG82636 Porcine PDGF BB ELISA kit User manual |
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