ARG83662
Rat CD25 ELISA Kit
Rat CD25 ELISA 试剂盒 for ELISA and Rat
概述
| 产品描述 | ARG83662 Rat CD25 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Rat CD25 in Serum, plasma (heparin, EDTA) and cell culture supernatants. |
|---|---|
| 反应物种 | Rat |
| 应用 | ELISA |
| 靶点名称 | CD25 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 50 pg/ml |
| 样品类型 | Serum, plasma (heparin, EDTA) and cell culture supernatants. |
| 标准范围 | 93.7 - 6000 pg/ml |
| 样本量 | 100 μl |
| 精确 | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
| 別名 | IL2RA; Interleukin 2 Receptor Subunit Alpha; CD25; Interleukin-2 Receptor Subunit Alpha; Interleukin 2 Receptor, Alpha; IL-2 Receptor Subunit Alpha; IL-2R Subunit Alpha; TAC Antigen; IDDM10; IL2R; P55; Insulin-Dependent Diabetes Mellitus 10; CD25 Antigen; IL-2-RA; IL2-RA; IMD41; TCGFR |
应用说明
| 检测时间 | 4 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 4°C, -20°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P26897 Rat Interleukin-2 receptor subunit alpha |
|---|---|
| 基因名称 | IL2RA |
| 全名 | interleukin 2 receptor, alpha |
| 背景介绍 | The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. Patients with severe Coronavirus Disease 2019 (COVID-19), the disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have significantly elevated levels of IL2R in their plasma. Similarly, serum IL-2R levels are found to be elevated in patients with different types of carcinomas. Certain IL2RA and IL2RB gene polymorphisms have been associated with lung cancer risk. [provided by RefSeq, Jul 2020] |
| 生物功能 | Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. [Uniprot] |
| 细胞定位 | Membrane. [Uniprot] |
| 翻译后修饰 | Disulfide bond, Glycoprotein. [Uniprot] |
检测图片 (1) Click the Picture to Zoom In
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ARG83662 Rat CD25 ELISA Kit standard curve image
ARG83662 Rat CD25 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
|---|---|
| ARG83662 Rat CD25 ELISA Kit User manual |
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