ARG82555

Rat GDNF Receptor alpha 2 ELISA Kit

Rat GDNF Receptor alpha 2 ELISA 试剂盒 for ELISA and Rat

内含物

货号 内含物名称 包装 温度
ARG82555-001 Antibody-coated microplate 8 X 12 strips 4°C. Unused strips should be sealed tightly in the air-tight pouch.
ARG82555-002 Standard 2 X 10 ng/vial 4°C
ARG82555-003 Standard/Sample diluent 30 ml (Ready to use) 4°C
ARG82555-004 Antibody conjugate concentrate (100X) 1 vial (100 µl) 4°C
ARG82555-005 Antibody diluent buffer 12 ml (Ready to use) 4°C
ARG82555-006 HRP-Streptavidin concentrate (100X) 1 vial (100 µl) 4°C
ARG82555-007 HRP-Streptavidin diluent buffer 12 ml (Ready to use) 4°C
ARG82555-008 25X Wash buffer 20 ml 4°C
ARG82555-009 TMB substrate 10 ml (Ready to use) 4°C (Protect from light)
ARG82555-010 STOP solution 10 ml (Ready to use) 4°C
ARG82555-011 Plate sealer 4 strips Room temperature

概述

产品描述 ARG82555 Rat GDNF Receptor alpha 2 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Rat GDNF Receptor alpha 2 in serum, plasma (EDTA, heparin, citrate) and cell culture supernatants.
反应物种 Rat
应用 ELISA
靶点名称 GDNF Receptor alpha 2
偶联标记 HRP
偶联标记说明 Substrate: TMB and read at 450 nm.
灵敏度 156 pg/ml
样品类型 Serum, plasma (EDTA, heparin, citrate) and cell culture supernatants.
标准范围 312 - 20000 pg/ml
样本量 100 µl
精确 Intra-Assay CV: 5.1%
Inter-Assay CV: 6.3%
別名 NRTNR-alpha; GDNFR-alpha-2; NRTNR-ALPHA; GFR-alpha-2; GDNFRB; RET ligand 2; GDNF receptor alpha-2; GDNFR-beta; TRNR2; NTNRA; NTNR-alpha; TGF-beta-related neurotrophic factor receptor 2; RETL2; GDNF receptor beta; Neurturin receptor alpha; GDNF family receptor alpha-2

应用说明

检测时间 ~ 5 hours

属性

形式 96 well
存放说明 Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

基因名称 GFRA2
全名 GDNF family receptor alpha 2
背景介绍 Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
生物功能 Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.

Isoform 2: Participates to NRTN-induced 'Ser-727' phosphorylation of STAT3. [UniProt]
细胞定位 Cell membrane; Lipid-anchor, GPI-anchor. [UniProt]
产品亮点 Related products:
GDNF Receptor antibodies; GDNF Receptor ELISA Kits;
New ELISA data calculation tool:
Simplify the ELISA analysis by GainData

检测图片 (1) Click the Picture to Zoom In

  • ARG82555 Rat GDNF Receptor alpha 2 ELISA Kit standard curve image

    ARG82555 Rat GDNF Receptor alpha 2 ELISA Kit results of a typical standard run with optical density reading at 450 nm.

Title Download Link
ARG82555 Rat GDNF Receptor alpha 2 ELISA Kit User manual download icon Download