ARG64720
anti-ACO1 / Aconitase 1 antibody
anti-ACO1 / Aconitase 1 antibody for Western blot and Human
Cell Biology and Cellular Response antibody; Gene Regulation antibody; Metabolism antibody; Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes ACO1 / Aconitase 1 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Cow |
| 应用 | WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ACO1 / Aconitase 1 |
| 抗原物种 | Human |
| 抗原 | C-QVDFNRRADSLQKNQ |
| 偶联标记 | Un-conjugated |
| 別名 | HEL60; Aconitase; EC 4.2.1.3; Cytoplasmic aconitate hydratase; Ferritin repressor protein; IRP1; Iron regulatory protein 1; IRE-BP 1; Iron-responsive element-binding protein 1; Citrate hydro-lyase; ACONS; IREB1; IREBP; IREBP1 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes. [provided by RefSeq, Jul 2008] |
| 产品亮点 | Related products: Aconitase antibodies; Aconitase ELISA Kits; Anti-Goat IgG secondary antibodies; Related news: TCA intermediate fumarate promotes mitobiogenesis |
| 研究领域 | Cell Biology and Cellular Response antibody; Gene Regulation antibody; Metabolism antibody; Signaling Transduction antibody |
| 预测分子量 | 98 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG64720 anti-ACO1 / Aconitase 1 antibody WB image
Western Blot: Human Liver lysate (35 µg protein in RIPA buffer) stained with ARG64720 anti-ACO1 / Aconitase 1 antibody at 0.1 µg/ml dilution.
