ARG43903
anti-ATF4 antibody
anti-ATF4 antibody for ELISA,Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ATF4 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ELISA, FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ATF4 |
| 抗原物种 | Human |
| 抗原 | Human ATF4 recombinant protein |
| 表达系统 | E.coli |
| 偶联标记 | Un-conjugated |
| Protein Full name | Cyclic AMP-dependent transcription factor ATF-4 |
| 別名 | ATF4; Activating Transcription Factor 4; CREB-2; TAXREB67; TXREB; Tax-Responsive Enhancer Element-Binding Protein 67; Cyclic AMP-Dependent Transcription Factor ATF-4; Cyclic AMP-Responsive Element-Binding Protein 2; CAMP-Dependent Transcription Factor ATF-4; CAMP-Responsive Element-Binding Protein 2; Tax-Responsive Enhancer Element B67; CREB2; Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67); CAMP Response Element-Binding Protein 2; DNA-Binding Protein TAXREB67; TaxREB67 |
应用说明
| 应用建议 |
|
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ATF4 |
| 全名 | Activating Transcription Factor 4 |
| 背景介绍 | This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. [provided by RefSeq, Sep 2011] |
| 生物功能 | Transcription factor that binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') and displays two biological functions, as regulator of metabolic and redox processes under normal cellular conditions, and as master transcription factor during integrated stress response (ISR). |
| 细胞定位 | Cell membrane, Cytoplasm, Cytoskeleton, Membrane, Nucleus |
| 预测分子量 | 39 kDa |
| 翻译后修饰 | Acetylation, Hydroxylation, Isopeptide bond, Phosphoprotein, Ubl conjugation |
检测图片 (5) Click the Picture to Zoom In
-
ARG43903 anti-ATF4 antibody ICC/IF image
Immunofluorescence: Hela cells stained with ARG43903 anti-ATF4 antibody antibody at 5 μg/ml dilution.
-
ARG43903 anti-ATF4 antibody WB image
Western blot: HepG2 stained with ARG43903 anti-ATF4 antibody at 0.5 μg/mL dilution.
-
ARG43903 anti-ATF4 antibody FACS image
Flow Cytometry: SiHa cells stained with ARG43903 anti-ATF4 antibody (blue) at 1 μg/1x10^6 cells dilution.
-
ARG43903 anti-ATF4 antibody WB image
Western blot: Rat brain stained with ARG43903 anti-ATF4 antibody at 0.5 μg/mL dilution.
-
ARG43903 anti-ATF4 antibody WB image
Western blot: Mouse brain stained with ARG43903 anti-ATF4 antibody at 0.5 μg/mL dilution.
