ARG57988
anti-AdipoR1 antibody
anti-AdipoR1 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes AdipoR1 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | AdipoR1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide derived from Human AdipoR1. |
| 偶联标记 | Un-conjugated |
| 別名 | CGI45; PAQR1; ACDCR1; Adiponectin receptor protein 1; TESBP1A; CGI-45; Progestin and adipoQ receptor family member I |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 阳性对照 | Human heart | ||||||||||
| 实际分子量 | ~ 43 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 150mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ADIPOR1 |
| 全名 | adiponectin receptor 1 |
| 背景介绍 | This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2014] |
| 生物功能 | Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism. Required for normal glucose and fat homeostasis and for maintaining a normal body weight. ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis. Has high affinity for globular adiponectin and low affinity for full-length adiponectin (By similarity). [UniProt] |
| 细胞定位 | Cell membrane; Multi-pass membrane protein. Note: Localized to the cell membrane and intracellular organelles. [UniProt] |
| 预测分子量 | 43 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG57988 anti-AdipoR1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human kidney stained with ARG57988 anti-AdipoR1 antibody.
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ARG57988 anti-AdipoR1 antibody WB image
Western blot: Human heart lysate stained with ARG57988 anti-AdipoR1 antibody.
