ARG55263
anti-Annexin A1 antibody
anti-Annexin A1 antibody for Western blot and Human,Mouse,Rat,Monkey
Signaling Transduction antibody
概述
| 产品描述 | Mouse Monoclonal antibody recognizes Annexin A1 |
|---|---|
| 反应物种 | Hu, Ms, Rat, Mk |
| 应用 | WB |
| 特异性 | This antibody detects endogenous levels of Annexin A1 and does not cross-react with related proteins. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | Annexin A1 |
| 抗原物种 | Human |
| 抗原 | Purified recombinant fragment of Human Annexin A1 (NP_000691.1). |
| 偶联标记 | Un-conjugated |
| 別名 | ANX1; Calpactin II; Phospholipase A2 inhibitory protein; Chromobindin-9; LPC1; Annexin-1; Annexin A1; Lipocortin I; Annexin I; p35; Calpactin-2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.4), 0.03% Proclin 300 and 50% Glycerol |
| 抗菌剂 | 0.03% Proclin 300 |
| 稳定剂 | 50% Glycerol |
| 浓度 | 4.85 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ANXA1 |
| 全名 | annexin A1 |
| 背景介绍 | This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. [provided by RefSeq, Dec 2014] |
| 生物功能 | Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity. [UniProt] |
| 细胞定位 | Nucleus. Cytoplasm. Cell projection > cilium. Basolateral cell membrane. [UniProt] |
| 研究领域 | Signaling Transduction antibody |
| 预测分子量 | 39 kDa |
| 翻译后修饰 | Phosphorylated by protein kinase C, EGFR and TRPM7 (PubMed:2457390, PubMed:15485879). Phosphorylated in response to EGF treatment (PubMed:2532504). Sumoylated. |
检测图片 (1) Click the Picture to Zoom In
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ARG55263 anti-Annexin A1 antibody WB image
Western blot: A549 cell lysate stained with ARG55263 anti-Annexin A1 antibody at 1:1000 dilution.
