ARG45690
anti-BCCIP antibody
anti-BCCIP antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes BCCIP |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | BCCIP |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human BCCIP. |
| 偶联标记 | Un-conjugated |
| 別名 | BCCIP; BRCA2 And CDKN1A Interacting Protein; BRCA2 And CDKN1A-Interacting Protein; BCCIPalpha; TOK-1; P21- And CDK-Associated Protein 1; Protein TOK-1; TOK1; BRCA2 And Cip1/P21 Interacting Protein; Cdk Inhibitor P21 Binding Protein; TOK-1alpha; BCCIPbeta; TOK-1beta |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | 45 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9CWI3 Mouse BRCA2 and CDKN1A-interacting protein Swiss-port # Q9P287 Human BRCA2 and CDKN1A-interacting protein |
|---|---|
| 基因名称 | BCCIP |
| 全名 | BRCA2 And CDKN1A Interacting Protein |
| 背景介绍 | This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | During interphase, required for microtubule organizing and anchoring activities. During mitosis, required for the organization and stabilization of the spindle pole. [UniProt] |
| 细胞定位 | Cytoplasm; Cytoskeleton; Nucleus. [UniProt] |
| 预测分子量 | 36 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
检测图片 (5) Click the Picture to Zoom In
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ARG45690 anti-BCCIP antibody ICC/IF image
Immunofluorescence: A549 stained with ARG45690 anti-BCCIP antibody at 5 μg/ml dilution.
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ARG45690 anti-BCCIP antibody WB image
Western blot: A431 stained with ARG45690 anti-BCCIP antibody at 0.5 μg/ml dilution.
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ARG45690 anti-BCCIP antibody FACS image
Flow Cytometry: CACO-2 stained with ARG45690 anti-BCCIP antibody at 1 µg/10^6 cells dilution.
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ARG45690 anti-BCCIP antibody IHC-P image
Immunohistochemistry: Rat testis stained with ARG45690 anti-BCCIP antibody at 2 μg/ml dilution.
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ARG45690 anti-BCCIP antibody IHC-P image
Immunohistochemistry: Mouse liver stained with ARG45690 anti-BCCIP antibody at 2 μg/ml dilution.
