ARG44785
anti-BLOC1S3 antibody
anti-BLOC1S3 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes BLOC1S3 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | BLOC1S3 |
| 抗原物种 | Human |
| 抗原表位 | LRRPETVVPG EATETDSERS ASSSEEEELY LGPSGPTRGR PTGLRVAGEA AETDSEPEPE PEPTAAPRDL PPLVVQRESA EEAWGTEEAP APAPARSLLQ LRLAESQARL DHDVAAAVSG |
| 偶联标记 | Un-conjugated |
| 別名 | BLOC1S3; Biogenesis Of Lysosomal Organelles Complex 1 Subunit 3; BLOS3; BLOC-1 Subunit 3; HPS8; Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 3; Biogenesis Of Lysosome-Related Organelles Complex-1, Subunit 3; Biogenesis Of Lysosome-Related Organelles Complex-1 Subunit 3; Reduced Pigmentation, Mouse, Homolog Of; Hermansky-Pudlak Syndrome 8 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q6QNY0 Human Biogenesis of lysosome-related organelles complex 1 subunit 3 |
|---|---|
| 基因名称 | BLOC1S3 |
| 全名 | Biogenesis Of Lysosomal Organelles Complex 1 Subunit 3 |
| 背景介绍 | This gene encodes a protein that is a component of the BLOC1 multi-subunit protein complex. This complex is necessary for the biogenesis of specialized organelles of the endosomal-lysosomal system, including platelet dense granules and melanosomes. Mutations in this gene cause Hermansky-Pudlak syndrome 8, a disease characterized by lysosomal storage defects, bleeding due to platelet storage pool deficiency, and oculocutaneous albinism. [provided by RefSeq, Jul 2008] |
| 生物功能 | Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. [Uniprot] |
| 细胞定位 | Cytoplasm. [Uniprot] |
| 翻译后修饰 | Phosphoprotein. [Uniprot] |
检测图片 (1) Click the Picture to Zoom In
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ARG44785 anti-BLOC1S3 antibody IHC-P image
Immunohistochemistry: Human spleen stained with ARG44785 anti-BLOC1S3 antibody at 10 µg/mL dilution.
