ARG66940
anti-Brachyury antibody [SQab22270]
anti-Brachyury antibody [SQab22270] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Recombinant Rabbit Monoclonal antibody [SQab22270] recognizes Brachyury |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | SQab22270 |
| 同位型 | IgG |
| 靶点名称 | Brachyury |
| 抗原物种 | Human |
| 抗原 | Recombinant Protein of Human Brachyury. |
| 偶联标记 | Un-conjugated |
| Protein Full name | T-box transcription factor T |
| 別名 | Protein T; TFT; Brachyury protein; SAVA |
应用说明
| 应用建议 |
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| 应用说明 | IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0). Incubate the samples at RT (18-25°C) for 30 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 阳性对照 | Human chordoma tissue |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05%BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | TBXT |
| 全名 | T-box transcription factor T |
| 背景介绍 | The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012] |
| 生物功能 | Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 47 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG66940 anti-Brachyury antibody [SQab22270] IHC-P image
Immunohistochemistry: Formalin/PFA-fixed and paraffin-embedded sections of Human chordoma tissue stained with ARG66940 anti-Brachyury antibody [SQab22270]. Antigen Retrieval: Heat tissue section in Tris-EDTA buffer (pH 9.0).
