概述

产品描述	Purification by Ion Exchange chromatography.
反应物种	Hu
应用	ELISA, IHC-P
宿主	Sheep
克隆	Polyclonal
同位型	IgG
靶点名称	C3d
抗原物种	Human
抗原	Purified C3d from human plasma.
偶联标记	Un-conjugated
別名	C3; Complement C3; CPAMD1; ARMD9; C3a; C3b; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 1; Complement Component C3a; Complement Component C3b; Complement Component 3; C3a Anaphylatoxin; Prepro-C3; Epididymis Secretory Sperm Binding Protein Li 62p; Acylation-Stimulating Protein Cleavage Product; HEL-S-62p; AHUS5; ASP

应用说明

应用建议	应用 推荐稀释比 ELISA Assay-dependent IHC-P 1:100
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purified C3d from pooled activated serum.
缓冲液	Glycine buffered saline, 0.1% EACA, 0.09% Sodium azide, 0.01% Benzamidine and 1mM EDTA.
抗菌剂	0.09% Sodium azide, 0.01% Benzamidine and 1mM EDTA
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 718 Human C3 Swiss-port # P01024 Human Complement C3
基因名称	C3
全名	Complement C3
背景介绍	Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015]
生物功能	C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates
细胞定位	Secreted
预测分子量	187 kDa
翻译后修饰	Cleavage on pair of basic residues, Disulfide bond, Glycoprotein, Phosphoprotein, Thioester bond

检测图片 (1) Click the Picture to Zoom In