ARG58328
anti-CAPZA2 antibody
anti-CAPZA2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
参考文献1
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CAPZA2 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CAPZA2 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-286 of Human CAPZA2 (NP_006127.1). |
| 偶联标记 | Un-conjugated |
| 別名 | F-actin-capping protein subunit alpha-2; CapZ alpha-2; CAPZ; CAPPA2 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | THP-1 | ||||||
| 实际分子量 | 38 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P47754 Mouse F-actin-capping protein subunit alpha-2 Swiss-port # P47755 Human F-actin-capping protein subunit alpha-2 |
|---|---|
| 基因名称 | CAPZA2 |
| 全名 | capping protein (actin filament) muscle Z-line, alpha 2 |
| 背景介绍 | The protein encoded by this gene is a member of the F-actin capping protein alpha subunit family. It is the alpha subunit of the barbed-end actin binding protein Cap Z. By capping the barbed end of actin filaments, Cap Z regulates the growth of the actin filaments at the barbed end. [provided by RefSeq, Jul 2008] |
| 生物功能 | F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. [UniProt] |
| 预测分子量 | 33 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG58328 anti-CAPZA2 antibody WB image
Western blot: 25 µg of THP-1 cell lysate stained with ARG58328 anti-CAPZA2 antibody at 1:1000 dilution.
文献引用
A structure-derived mechanism reveals how capping protein promotes nucleation in branched actin networks.
WB / Mouse
