ARG56634
anti-CCL21 / Exodus 2 antibody
anti-CCL21 / Exodus 2 antibody for ELISA,Neutralizing,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CCL21 / Exodus 2 |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, Neut, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CCL21 / Exodus 2 |
| 抗原物种 | Human |
| 抗原 | E.coli derived Recombinant Human Exodus2. (SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGC RKDRGASKTG KKGKGSKGCR KTERSQTPKG P) |
| 偶联标记 | Un-conjugated |
| 別名 | TCA4; Small-inducible cytokine A21; Beta-chemokine exodus-2; ECL; SCYA21; Secondary lymphoid-tissue chemokine; CKb9; 6Ckine; C-C motif chemokine 21; SLC |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CCL21 |
| 全名 | chemokine (C-C motif) ligand 21 |
| 背景介绍 | This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). [provided by RefSeq, Sep 2014] |
| 生物功能 | Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. [UniProt] |
| 预测分子量 | 15 kDa |
检测图片 (5) Click the Picture to Zoom In
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ARG56634 anti-CCL21 / Exodus 2 antibody WB image
Western blot: 250 - 0.24 ng of Human Exodus-2 stained with ARG56634 anti-CCL21 / Exodus 2 antibody, under reducing conditions.
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ARG56634 anti-CCL21 / Exodus 2 antibody WB image
Western blot: 250 - 0.24 ng of Human Exodus-2 stained with ARG56634 anti-CCL21 / Exodus 2 antibody, under reducing conditions.
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ARG56634 anti-CCL21 / Exodus 2 antibody WB image
Western blot: 250 - 0.24 ng of Human Exodus-2 stained with ARG56634 anti-CCL21 / Exodus 2 antibody, under non-reducing conditions.
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ARG56634 anti-CCL21 / Exodus 2 antibody WB image
Western blot: 250 - 0.24 ng of Human Exodus-2 stained with ARG56634 anti-CCL21 / Exodus 2 antibody, under non-reducing conditions.
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ARG56634 anti-CCL21 / Exodus 2 antibody standard curve image
Sandwich ELISA: ARG56634 anti-CCL21 / Exodus 2 antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with ARG56744 anti-CCL21 / Exodus2 antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density.
