ARG66041
anti-CCL23 antibody
anti-CCL23 antibody for ELISA,Neutralizing,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CCL23 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ELISA, Neut, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CCL23 |
| 抗原物种 | Human |
| 抗原 | E. coli derived recombinant Human CCL23. (RVTKDAETEF MMSKLPLENP VLLDRFHATS ADCCISYTPR SIPCSLLESY FETNSECSKP GVIFLTKKGR RFCANPSDKQ VQVCMRMLKL DTRIKTRKN) |
| 偶联标记 | Un-conjugated |
| 別名 | Ckb-8-1; CK-beta-8; CKB-8; 27-99; CK-BETA-8; 30-99; SCYA23; CKb8; 22-99; Small-inducible cytokine A23; C-C motif chemokine 23; MPIF-1; hmrp-2a; MIP3; Myeloid progenitor inhibitory factor 1; Macrophage inflammatory protein 3; 19-99; Ckb-8; MIP-3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CCL23 |
| 全名 | chemokine (C-C motif) ligand 23 |
| 背景介绍 | This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013] |
| 生物功能 | Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23. [UniProt] |
| 预测分子量 | 13 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG66041 anti-CCL23 antibody WB image
Western blot: 250 - 0.24 ng of Human MIP-3 stained with ARG66041 anti-CCL23 antibody, under reducing conditions.
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ARG66041 anti-CCL23 antibody standard curve image
Sandwich ELISA: ARG66041 anti-CCL23 antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with ARG66042 anti-CCL23 antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density reading at 405 - 650 nm.
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ARG66041 anti-CCL23 antibody WB image
Western blot: 250 - 0.24 ng of Human MIP-3 stained with ARG66041 anti-CCL23 antibody, under non-reducing conditions.
