ARG21106
anti-CD102 / ICAM2 antibody [3C4] (low endotoxin)
anti-CD102 / ICAM2 antibody [3C4] (low endotoxin) for Blocking,Flow cytometry,ICC/IF,IHC-Frozen sections,Immunoprecipitation and Mouse
概述
| 产品描述 | Azide free and low endotoxin Rat Monoclonal antibody [3C4] recognizes CD102 / ICAM2 |
|---|---|
| 反应物种 | Ms |
| 应用 | BL, FACS, ICC/IF, IHC-Fr, IP |
| 特异性 | Mouse CD102. The clone 3C4 reacts with the cell surface glycoprotein mouse CD102 (ICAM-2), a ligand for the leucocyte integrin CD11a/CD18 (LFA-1). CD102 is constitutively expressed on T cells, B cells, and at high levels on vascular endothelial cells. It is also expressed on a variety of leukocyte cell lines. The 3C4 antibody blocks the interaction between ICAM-2 and LFA-1. |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | 3C4 |
| 同位型 | IgG2a, kappa |
| 靶点名称 | CD102 / ICAM2 |
| 抗原物种 | Mouse |
| 抗原 | COS cells transfected with mouse ICAM-2 cDNA and BW5147 AKR/J mouse thymoma cell line |
| 偶联标记 | Un-conjugated |
| 別名 | CD102; CD antigen CD102; Intercellular adhesion molecule 2; ICAM-2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化说明 | Low endotoxin |
| 缓冲液 | PBS |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ICAM2 |
| 全名 | intercellular adhesion molecule 2 |
| 背景介绍 | The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. [UniProt] |
| 预测分子量 | 31 kDa |
