ARG66538
anti-CD125 / IL5RA antibody
anti-CD125 / IL5RA antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CD125 / IL5RA |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CD125 / IL5RA |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the N-terminal region of Human CD125 / IL5RA. |
| 偶联标记 | Un-conjugated |
| 別名 | CD125; CDw125; IL-5 receptor subunit alpha; IL5R; Interleukin-5 receptor subunit alpha; CD antigen CD125; HSIL5R3; IL-5R-alpha; IL-5R subunit alpha; IL-5RA |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol and 0.5% BSA |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q01344 Human Interleukin-5 receptor subunit alpha |
|---|---|
| 基因名称 | IL5RA |
| 全名 | interleukin 5 receptor, alpha |
| 背景介绍 | The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq, Jul 2011] |
| 生物功能 | This is the receptor for interleukin-5. The alpha chain binds to IL5. [UniProt] |
| 细胞定位 | Membrane; Single-pass type I membrane protein. [UniProt] |
| 预测分子量 | 48 kDa |
检测图片 (1) Click the Picture to Zoom In
-
ARG66538 anti-CD125 / IL5RA antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human brain tissue stained with ARG66538 anti-CD125 / IL5RA antibody.
