ARG42400
anti-CD129 / IL9R antibody [AH9R7] (PE)
anti-CD129 / IL9R antibody [AH9R7] (PE) for Flow cytometry and Human
概述
| 产品描述 | PE-conjugated Mouse Monoclonal antibody [AH9R7] recognizes CD129 / IL9R |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS |
| 特异性 | The mouse monoclonal antibody AH9R7 recognizes an extracellular epitope of CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | AH9R7 |
| 同位型 | IgG2b, kappa |
| 靶点名称 | CD129 / IL9R |
| 抗原物种 | Human |
| 抗原 | Human CD129-transfected cell line. |
| 偶联标记 | PE |
| 別名 | IL-9R; CD antigen CD129; CD129; IL-9 receptor; Interleukin-9 receptor |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified |
| 缓冲液 | PBS and 15 mM Sodium azide. |
| 抗菌剂 | 15 mM Sodium azide |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | IL9R |
| 全名 | interleukin 9 receptor |
| 背景介绍 | The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | This is a receptor for interleukin-9. [UniProt] |
| 细胞定位 | Cell membrane; Single-pass type I membrane protein. Secreted. [UniProt] |
| 预测分子量 | 57 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG42400 anti-CD129 / IL9R antibody [AH9R7] (PE) FACS image
Flow Cytometry: Separation of stained HuT-78 cells (red) from unstained HuT-78 cells (grey). Cells were stained with ARG42400 anti-CD129 / IL9R antibody [AH9R7] (PE) at 9 µg/ml dilution.
