ARG58043
anti-CD197 / CCR7 antibody
anti-CD197 / CCR7 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CD197 / CCR7 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CD197 / CCR7 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide derived from Human CD197 / CCR7. |
| 偶联标记 | Un-conjugated |
| 別名 | C-C chemokine receptor type 7; CD197; CD antigen CD197; CCR-7; CC-CKR-7; BLR2; CMKBR7; C-C CKR-7; MIP-3 beta receptor; EBV-induced G-protein coupled receptor 1; EBI1; Epstein-Barr virus-induced G-protein coupled receptor 1; CDw197 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 阳性对照 | Daudi and MCF-7 | ||||||||||
| 实际分子量 | ~ 42 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CCR7 |
| 全名 | chemokine (C-C motif) receptor 7 |
| 背景介绍 | The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014] |
| 生物功能 | Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions. [UniProt] |
| 细胞定位 | Cell membrane > Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 43 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG58043 anti-CD197 / CCR7 antibody ICC/IF image
Immunofluorescence: HeLa cells stained with ARG58043 anti-CD197 / CCR7 antibody (green). DAPI (blue) nuclear stain.
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ARG58043 anti-CD197 / CCR7 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human spleen tissue stained with ARG58043 anti-CD197 / CCR7 antibody.
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ARG58043 anti-CD197 / CCR7 antibody WB image
Western blot: Daudi and MCF-7 cell lysates stained with ARG58043 anti-CD197 / CCR7 antibody.
