ARG21281
anti-CD20 antibody [B-Ly1], F(ab')2 fragment
anti-CD20 antibody [B-Ly1], F(ab')2 fragment for Blocking,Flow cytometry,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation and Human
Cancer antibody; Developmental Biology antibody; Immune System antibody; B cell Marker antibody; Immature B Cell Marker antibody; Inflammatory Cell Marker antibody; Tumor-infiltrating Lymphocyte Study antibody
概述
| 产品描述 | F(ab'2) fragment of Mouse Monoclonal antibody [B-Ly1] recognizes CD20 |
|---|---|
| 反应物种 | Hu |
| 应用 | BL, FACS, IHC-Fr, IHC-P, IP |
| 特异性 | Human CD20 |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | B-Ly1 |
| 同位型 | F(ab')2 IgG1, kappa |
| 靶点名称 | CD20 |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | Bp35; LEU-16; B-lymphocyte surface antigen B1; B-lymphocyte antigen CD20; CD20; S7; CD antigen CD20; Leukocyte surface antigen Leu-16; B1; CVID5; Membrane-spanning 4-domains subfamily A member 1; MS4A2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | BBS (pH 8.2) |
| 浓度 | 0.1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MS4A1 |
| 全名 | membrane-spanning 4-domains, subfamily A, member 1 |
| 背景介绍 | CD20 is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008] |
| 生物功能 | CD20 is a B-lymphocyte-specific membrane protein. It plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes (PubMed:3925015, PubMed:7684739, PubMed:12920111). Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR (PubMed:7684739, PubMed:12920111, PubMed:18474602). [UniProt] |
| 产品亮点 | Related products: CD20 antibodies; CD20 ELISA Kits; CD20 Duos / Panels; Anti-Mouse F(a secondary antibodies; Related news: New antibody panels and duos for Tumor immune microenvironment Tumor-Infiltrating Lymphocytes (TILs) Exploring Antiviral Immune Response |
| 研究领域 | Cancer antibody; Developmental Biology antibody; Immune System antibody; B cell Marker antibody; Immature B Cell Marker antibody; Inflammatory Cell Marker antibody; Tumor-infiltrating Lymphocyte Study antibody |
| 预测分子量 | 33 kDa |
| 翻译后修饰 | Phosphorylated. Might be functionally regulated by protein kinase(s). |
检测图片 (1) Click the Picture to Zoom In
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ARG21281 anti-CD20 antibody [B-Ly1], F(ab')2 fragment FACS image
Flow Cytometry: Human peripheral blood lymphocytes stained with ARG21281 anti-CD20 antibody [B-Ly1], F(ab')2 fragment followed by ARG23759 Goat anti-Mouse IgG (H+L) antibody (PE) (pre-adsorbed).
