ARG62768

anti-CD20 antibody [LT20]

Datasheet

订购信息

包装

价格 (USD)

100 μg

399

arigo in CHINA:
恩瑞科生物
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0571-8708-1890

概述

产品描述	Mouse Monoclonal antibody [LT20] recognizes CD20
反应物种	Hu
应用	FACS
特异性	The clone LT20 reacts with CD20 (Bp35), a 33-37 kDa non-glycosylated membrane receptor with four transmembrane domains, expressed on B lymphocytes (it is lost on plasma cells), follicular dendritic cells, and at low levels on peripheral blood T lymphocytes.
宿主	Mouse
克隆	Monoclonal
克隆号	LT20
同位型	IgG2a
靶点名称	CD20
抗原物种	Human
抗原	Normal human lymphocytes from lymph node.
偶联标记	Un-conjugated
別名	Bp35; LEU-16; B-lymphocyte surface antigen B1; B-lymphocyte antigen CD20; CD20; S7; CD antigen CD20; Leukocyte surface antigen Leu-16; B1; CVID5; Membrane-spanning 4-domains subfamily A member 1; MS4A2

应用说明

应用建议

应用	推荐稀释比
FACS	3 µg/ml

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purified from ascites by precipitation methods and ion exchange chromatography.
纯度	> 95% (by SDS-PAGE)
缓冲液	PBS (pH 7.4) and 15 mM Sodium azide
抗菌剂	15 mM Sodium azide
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 931 Human MS4A1 Swiss-port # P11836 Human B-lymphocyte antigen CD20
基因名称	MS4A1
全名	membrane-spanning 4-domains, subfamily A, member 1
背景介绍	CD20 is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008]
生物功能	CD20 is a B-lymphocyte-specific membrane protein. It plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes (PubMed:3925015, PubMed:7684739, PubMed:12920111). Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR (PubMed:7684739, PubMed:12920111, PubMed:18474602). [UniProt]
产品亮点	Related products: CD20 antibodies; CD20 ELISA Kits; CD20 Duos / Panels; Anti-Mouse IgG secondary antibodies; Related news: New antibody panels and duos for Tumor immune microenvironment Tumor-Infiltrating Lymphocytes (TILs) Exploring Antiviral Immune Response
研究领域	Cancer antibody; Developmental Biology antibody; Immune System antibody; B cell Marker antibody; Immature B Cell Marker antibody; Inflammatory Cell Marker antibody; Tumor-infiltrating Lymphocyte Study antibody
预测分子量	33 kDa
翻译后修饰	Phosphorylated. Might be functionally regulated by protein kinase(s).

检测图片 (2) Click the Picture to Zoom In

ARG62768 anti-CD20 antibody [LT20] FACS image

Flow Cytometry: Human peripheral blood stained with ARG62768 anti-CD20 antibody [LT20] at 10 µg/ml dilution, followed by APC-conjugated Goat anti-Mouse antibody.
ARG62768 anti-CD20 antibody [LT20] FACS image

Flow Cytometry: Separation of human CD20 positive lymphocytes (red-filled) from neutrophil granulocytes (black-dashed), Human peripheral whole blood stained with ARG62768 anti-CD20 antibody [LT20] at 10 µg/ml dilution, followed by APC-conjugated Goat anti-Mouse antibody.