ARG54293

anti-CD200 antibody [OX-104] (PE)

Datasheet

订购信息

包装

价格 (USD)

50 tests

335

arigo in CHINA:
恩瑞科生物
☎ 400-886-0853,
0571-8708-1890

概述

产品描述	PE-conjugated Mouse Monoclonal antibody [OX-104] recognizes CD200
反应物种	Hu
应用	FACS
特异性	The clone OX-104 recognizes CD200, a type-1 glycoprotein of the immunoglobulin superfamily, which is expressed in neurons, B and T cell subsets, keratinocytes, follicular dendritic cells, and ovarian cells.
宿主	Mouse
克隆	Monoclonal
克隆号	OX-104
同位型	IgG1
靶点名称	CD200
抗原物种	Human
抗原	Human CD200
偶联标记	PE
別名	OX-2; OX-2 membrane glycoprotein; MOX1; MOX2; CD antigen CD200; MRC

应用说明

应用建议

应用	推荐稀释比
FACS	10 µl / 10^6 cells

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化说明	The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
缓冲液	PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
抗菌剂	15 mM Sodium azide
稳定剂	0.2% (w/v) high-grade protease free BSA
存放说明	Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 4345 Human CD200 Swiss-port # P41217 Human OX-2 membrane glycoprotein
基因名称	CD200
全名	CD200 molecule
背景介绍	CD200 (also known as OX2 or MRC) is a type-1 membrane glycoprotein, which contains two extracellular immunoglobulin domains, transmembrane domain and cytoplasmic domain. It is expressed by neuronal cells, B and T cell subsets, follicular dendritic cells, keratinocytes, and ovarian cells. The interaction between CD200 and its receptor CD200R results in macrophage activation (IL-6 production), inhibition of mast cell degranulation along with reduced TNF-alpha and IL-13 secretion and overall attenuation of the activation status of lymphocytes. It seems CD200 is also involved in maternal tolerance and its decreased expression in hair follicle correlates with follicular miniaturization.
生物功能	Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues. [UniProt]
研究领域	Cell Biology and Cellular Response antibody; Immune System antibody
预测分子量	31 kDa

检测图片 (4) Click the Picture to Zoom In

ARG54293 anti-CD200 antibody [OX-104] (PE) FACS image

Flow Cytometry: Human peripheral whole blood stained with ARG54293 anti-CD200 antibody [OX-104] (PE) (10 µl reagent / 100 µl of peripheral whole blood).
ARG54293 anti-CD200 antibody [OX-104] (PE) FACS image

Flow Cytometry: Human lymphocytes stained with ARG54293 anti-CD200 antibody [OX-104] (PE) (10 µl reagent / 100 µl of peripheral whole blood) and ARG53782 anti-CD19 antibody [LT19] (APC) (10 µl reagent / 100 µl of peripheral whole blood).
ARG54293 anti-CD200 antibody [OX-104] (PE) FACS image

Flow Cytometry: Separation of human CD200 positive B cells (red-filled) from neutrophil granulocytes (black-dashed). Human peripheral whole blood stained with ARG54293 anti-CD200 antibody [OX-104] (PE) (10 µl reagent / 100 µl of peripheral whole blood).
ARG54293 anti-CD200 antibody [OX-104] (PE) FACS image

Flow Cytometry: Human lymphocytes stained with ARG54293 anti-CD200 antibody [OX-104] (PE) (10 µl reagent / 100 µl of peripheral whole blood) and ARG54302 anti-CD3 antibody [UCHT1] (APC) (10 µl reagent / 100 µl of peripheral whole blood).