ARG23467
anti-CD200 antibody [OX-2]
anti-CD200 antibody [OX-2] for Electron microscopy,Flow cytometry,ICC/IF,IHC-Frozen sections,Immunoprecipitation and Rat
概述
| 产品描述 | Mouse Monoclonal antibody [OX-2] recognizes CD200 Mouse anti Rat CD200 antibody, clone OX-2 recognizes the rat CD200 cell surface antigen, also known as OX-2, a type I membrane glycoprotein, expressed on rat thymocytes, neurons, follicular dendritic cells, endothelium and at low levels on some B cells and smooth muscle cells.Studies have indicated that the CD200-CD200 ligand system is important in the control of macrophage and granulocyte activation and that this antibody blocks OX-2 mediated T cell costimulation (Ko et al. 2009).This product is routinely tested by flow cytometry on rat thymocytes. |
|---|---|
| 反应物种 | Rat |
| 应用 | EM, FACS, ICC/IF, IHC-Fr, IP |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | OX-2 |
| 同位型 | IgG1 |
| 靶点名称 | CD200 |
| 抗原物种 | Rat |
| 抗原 | Rat thymocyte membrane glycoproteins. |
| 偶联标记 | Un-conjugated |
| 別名 | OX-2; OX-2 membrane glycoprotein; MOX1; MOX2; CD antigen CD200; MRC |
应用说明
| 应用建议 |
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| 应用说明 | FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS and 0.09% Sodium azide. |
| 抗菌剂 | 0.09% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | CD200 |
|---|---|
| 全名 | CD200 molecule |
| 背景介绍 | The protein encoded by this gene is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues. [UniProt] |
| 预测分子量 | 31 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG23467 anti-CD200 antibody [OX-2] FACS image
Flow Cytometry: Rat thymocytes stained with ARG23467 anti-CD200 antibody [OX-2].
