ARG59260
anti-CD201 / EPCR antibody
anti-CD201 / EPCR antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CD201 / EPCR |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CD201 / EPCR |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 19-209 of Human CD201 / EPCR (NP_006395.2). |
| 偶联标记 | Un-conjugated |
| 別名 | CD antigen CD201; Activated protein C receptor; EPCR; APC receptor; CCCA; Endothelial cell protein C receptor; CCD41; Endothelial protein C receptor |
应用说明
| 预测反应性说明 | Mouse | ||||||
|---|---|---|---|---|---|---|---|
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | THP-1 | ||||||
| 实际分子量 | 50 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PROCR |
| 全名 | protein C receptor, endothelial |
| 背景介绍 | The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. [provided by RefSeq, Jul 2013] |
| 生物功能 | Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation. [UniProt] |
| 细胞定位 | Membrane; Single-pass type I membrane protein. [UniProt] |
| 预测分子量 | 27 kDa |
| 翻译后修饰 | N-glycosylated. A soluble form exists; probably released by a metalloprotease. Seems to have the same activity as the membrane-bound form. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG59260 anti-CD201 / EPCR antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat liver stained with ARG59260 anti-CD201 / EPCR antibody at 1:200 dilution.
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ARG59260 anti-CD201 / EPCR antibody WB image
Western blot: 25 µg of THP-1 cell lysate stained with ARG59260 anti-CD201 / EPCR antibody at 1:1000 dilution.
