ARG21135
anti-CD21 antibody [BB6-11C9.6] (FITC)
anti-CD21 antibody [BB6-11C9.6] (FITC) for Flow cytometry,IHC-Frozen sections and Pig
概述
| 产品描述 | FITC-conjugated Mouse Monoclonal antibody [BB6-11C9.6] recognizes CD21 |
|---|---|
| 反应物种 | Pig |
| 应用 | FACS, IHC-Fr |
| 特异性 | Porcine CD21. The clone BB6-11C9.6 stains the following percentages of surface immunoglobulin (sIg) positive cells in porcine lymphoid tissues - 92-96% in peripheral blood, 74-98% in mesenteric lymph nodes, 97-100% in ileal Peyer’s patches (ILPP), 93-97% in spleen, and 0% in thymus. The antibody does not stain B cells in cord blood or spleen from pig fetuses (105 days gestation). |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | BB6-11C9.6 |
| 同位型 | IgG1, kappa |
| 靶点名称 | CD21 |
| 抗原物种 | Pig |
| 偶联标记 | FITC |
| 別名 | Cr2; Complement C3d receptor; C3DR; CD21; CD antigen CD21; Complement receptor type 2; SLEB9; CR; CVID7; Epstein-Barr virus receptor; EBV receptor |
应用说明
| 应用建议 |
|
||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | PBS and 0.1% Sodium azide. |
| 抗菌剂 | 0.1% Sodium azide |
| 浓度 | 0.5 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | CR2 |
|---|---|
| 全名 | complement component (3d/Epstein Barr virus) receptor 2 |
| 背景介绍 | CD21 (complement receptor 2, CR2) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands. |
| 生物功能 | Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation. [UniProt] |
| 预测分子量 | 113 kDa |
