ARG58750
anti-CD223 / LAG3 antibody [1G4]
anti-CD223 / LAG3 antibody [1G4] for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal [1G4] antibody recognizes CD223 / LAG3 |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 1G4 |
| 同位型 | IgG1, kappa |
| 靶点名称 | CD223 / LAG3 |
| 抗原物种 | Human |
| 抗原 | Extracellular domain of Human CD223 / LAG3. |
| 偶联标记 | Un-conjugated |
| 別名 | CD antigen CD223; CD223; Protein FDC; Lymphocyte activation gene 3 protein; LAG-3 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | Human lymphoma tissue and spleen tissue. | ||||||||
| 实际分子量 | ~ 60, 70, 80 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P18627 Human Lymphocyte activation gene 3 protein |
|---|---|
| 基因名称 | LAG3 |
| 全名 | lymphocyte-activation gene 3 |
| 背景介绍 | Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008] |
| 生物功能 | Involved in lymphocyte activation. Binds to HLA class-II antigens. [UniProt] |
| 预测分子量 | 57 kDa |
检测图片 (5) Click the Picture to Zoom In
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ARG58750 anti-CD223 / LAG3 antibody [1G4] IF image
Immunofluorescence: LAG3 over expressing HEK293 cells stained with ARG58750 anti-CD223 / LAG3 antibody [1G4] at 2 µg/ml dilution.
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ARG58750 anti-CD223 / LAG3 antibody [1G4] IHC image
Immunohistochemistry: LAG3 over expressing Human spleen tissue stained with ARG58750 anti-CD223 / LAG3 antibody [1G4] at 10 µg/ml dilution.
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ARG58750 anti-CD223 / LAG3 antibody [1G4] WB image
Western blot: LAG3 over expressing HEK293 cells stained with ARG58750 anti-CD223 / LAG3 antibody [1G4] at 0.25, 0.5 and 1 µg/ml dilution.
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ARG58750 anti-CD223 / LAG3 antibody [1G4] ICC image
Immunocytochemistry: LAG3 over expressing HEK293 cells stained with ARG58750 anti-CD223 / LAG3 antibody [1G4]. Lower left (control): Mouse IgG antibody at 1 µg/ml dilution.
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ARG58750 anti-CD223 / LAG3 antibody [1G4] IHC-P image
Immunohistochemistry: Human lymphoma tissue stained with ARG58750 anti-CD223 / LAG3 antibody [1G4]. Lower left (control): Mouse IgG at 5 µg/ml dilution.
