ARG58749
anti-CD223 / LAG3 antibody [2G8]
anti-CD223 / LAG3 antibody [2G8] for Flow cytometry,ICC/IF,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal [2G8] antibody recognizes CD223 / LAG3 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 2G8 |
| 同位型 | IgG1, kappa |
| 靶点名称 | CD223 / LAG3 |
| 抗原物种 | Human |
| 抗原 | Extracellular domain of Human CD223 / LAG3. |
| 偶联标记 | Un-conjugated |
| 別名 | CD antigen CD223; CD223; Protein FDC; Lymphocyte activation gene 3 protein; LAG-3 |
应用说明
| 应用建议 |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | Human lymphoma tissue and spleen tissue. | ||||||||
| 实际分子量 | ~ 80 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P18627 Human Lymphocyte activation gene 3 protein |
|---|---|
| 基因名称 | LAG3 |
| 全名 | lymphocyte-activation gene 3 |
| 背景介绍 | Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008] |
| 生物功能 | Involved in lymphocyte activation. Binds to HLA class-II antigens. [UniProt] |
| 预测分子量 | 57 kDa |
检测图片 (4) Click the Picture to Zoom In
-
ARG58749 anti-CD223 / LAG3 antibody [2G8] IF image
Immunofluorescence: LAG3 over expressing HEK293 cells stained with ARG58749 anti-CD223 / LAG3 antibody [2G8] at 2 µg/ml dilution.
-
ARG58749 anti-CD223 / LAG3 antibody [2G8] FACS image
Flow Cytometry: LAG3 over expressing HEK293 cells stained with ARG58749 anti-CD223 / LAG3 antibody [2G8] at 1 µg/ml dilution. Blue: Untransfected HEK293 cells. Yellow: LAG-3 over expressing HEK293 cells.
-
ARG58749 anti-CD223 / LAG3 antibody [2G8] WB image
Western blot: LAG3 over expressing HEK293 cells stained with ARG58749 anti-CD223 / LAG3 antibody [2G8] at 0.25, 0.5 and 1 µg/ml dilution.
-
ARG58749 anti-CD223 / LAG3 antibody [2G8] ICC image
Immunocytochemistry: LAG3 over expressing HEK293 cells stained with ARG58749 anti-CD223 / LAG3 antibody [2G8]. Lower left (control): Mouse IgG antibody at 1 µg/ml dilution.
