ARG23890
anti-CD23 antibody [Tu1] (FITC)
anti-CD23 antibody [Tu1] (FITC) for Blocking,Flow cytometry,ICC/IF,IHC-Frozen sections,Western blot and Human
概述
| 产品描述 | FITC-conjugated Mouse Monoclonal antibody [Tü1] recognizes CD23 |
|---|---|
| 反应物种 | Hu |
| 应用 | BL, FACS, ICC/IF, IHC-Fr, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | Tü1 |
| 同位型 | IgG3, kappa |
| 靶点名称 | CD23 |
| 抗原物种 | Human |
| 抗原 | Purified Human tonsil lymphocytes (KR3598 cells). |
| 偶联标记 | FITC |
| 別名 | CD23A; BLAST-2; Lymphocyte IgE receptor; CLEC4J; Immunoglobulin E-binding factor; CD23; IGEBF; Fc-epsilon-RII; CD antigen CD23; FCE2; Low affinity immunoglobulin epsilon Fc receptor; C-type lectin domain family 4 member J |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS and 0.1% Sodium azide |
| 抗菌剂 | 0.1% Sodium azide |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P06734 Human Low affinity immunoglobulin epsilon Fc receptor |
|---|---|
| 基因名称 | FCER2 |
| 全名 | Fc fragment of IgE, low affinity II, receptor for (CD23) |
| 背景介绍 | The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011] |
| 生物功能 | Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen). [UniProt] |
| 细胞定位 | Cell membrane; Single-pass type II membrane protein. Cell membrane; Lipid-anchor. Secreted. Note=Also exists as a soluble excreted form, sCD23. [UniProt] |
| 预测分子量 | 36 kDa |
| 翻译后修饰 | N- and O-glycosylated. The secreted form sCD23 is produced by ADAM10-mediated ectodomain shedding. [UniProt] |
