ARG20881
anti-CD25 antibody [7D4] (Biotin)
anti-CD25 antibody [7D4] (Biotin) for Blocking,Depletion,Flow cytometry,IHC-Frozen sections,Neutralizing and Mouse
Immune System antibody; Pre-B Cell Marker antibody
概述
| 产品描述 | Biotin-conjugated Rat Monoclonal antibody [7D4] recognizes CD25 |
|---|---|
| 反应物种 | Ms |
| 应用 | BL, Depletion, FACS, IHC-Fr, Neut |
| 特异性 | Mouse CD25. The clone 7D4 reacts with an epitope between amino acids 125 and 212 that is distinct from that recognized by The clone 3C7. While The clone 7D4 does not block the binding of IL-2 to CD25, when used in combination with The clone 3C7 it results in higher levels of inhibition of IL-2-driven proliferation than either of these two monoclonal antibodies alone. |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | 7D4 |
| 同位型 | IgM, kappa |
| 靶点名称 | CD25 |
| 抗原物种 | Mouse |
| 抗原 | IL-2 dependent BALB/c helper T cell clone HT2 |
| 偶联标记 | Biotin |
| 別名 | IL-2-RA; IL-2 receptor subunit alpha; CD25; TCGFR; TAC antigen; IL2R; CD antigen CD25; Interleukin-2 receptor subunit alpha; IL-2R subunit alpha; p55; IL2-RA; IDDM10 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | PBS and 0.1% Sodium azide. |
| 抗菌剂 | 0.1% Sodium azide |
| 浓度 | 0.5 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P01590 Mouse Interleukin-2 receptor subunit alpha |
|---|---|
| 基因名称 | IL2RA |
| 全名 | interleukin 2 receptor, alpha chain |
| 背景介绍 | The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009] |
| 生物功能 | Receptor for interleukin-2. [UniProt] |
| 研究领域 | Immune System antibody; Pre-B Cell Marker antibody |
| 预测分子量 | 31 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG20881 anti-CD25 antibody [7D4] (Biotin) FACS image
Flow Cytometry: C57BL/6 Mouse cytotoxic T lymphocyte cell line CTLL-2 was stained with ARG20881 anti-CD25 antibody [7D4] (Biotin) followed by Streptavidin (FITC).
