ARG62407
anti-CD25 antibody [IL2R.1]
anti-CD25 antibody [IL2R.1] for Flow cytometry,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections and Human
Immune System antibody; Pre-B Cell Marker antibody
概述
| 产品描述 | Mouse Monoclonal antibody [IL2R.1] recognizes CD25 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, IHC-Fr, IHC-P |
| 特异性 | Specific to a 55 kDa protein known as interleukin 2-receptor (IL-2R alpha). IL-2R alpha is over expressed on the surface of activated T cell, HTLV-1 or HTLV-2 positive T cell lines and moderately expressed on activated B cells, NK-cells and macrophages. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | IL2R.1 |
| 同位型 | IgG1 |
| 靶点名称 | CD25 |
| 抗原物种 | Human |
| 抗原 | BALB/C mice were injected with recombinant human interleukin-2 receptor |
| 偶联标记 | Un-conjugated |
| 別名 | IL-2-RA; IL-2 receptor subunit alpha; CD25; TCGFR; TAC antigen; IL2R; CD antigen CD25; Interleukin-2 receptor subunit alpha; IL-2R subunit alpha; p55; IL2-RA; IDDM10 |
应用说明
| 应用说明 | FACS: 1/50. IHC-P: 1/20 - 1/50. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
|---|---|
| 阳性对照 | Tonsil |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purified |
| 缓冲液 | PBS (pH 7.2), 0.2% BSA and 0.09% Sodium azide |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 0.2% BSA |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P01589 Human Interleukin-2 receptor subunit alpha |
|---|---|
| 基因名称 | IL2RA |
| 全名 | interleukin 2 receptor, alpha |
| 背景介绍 | The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009] |
| 生物功能 | Receptor for interleukin-2. [UniProt] |
| 细胞定位 | Membrane. |
| 研究领域 | Immune System antibody; Pre-B Cell Marker antibody |
| 预测分子量 | 31 kDa |
克隆号文献
CD25 is a novel marker of hepatic bile canaliculus.
IHC / Human
FOXP3 T regulatory cells in lesions of oral lichen planus correlated with disease activity.
IHC / Human
Regulatory T cells and liver pathology in a murine graft versus host response model.
IHC / Mouse
Pathway analysis of coronary atherosclerosis.
IHC-Fr / Human
Focal complex formation in adult cardiomyocytes is accompanied by the activation of beta3 integrin and c-Src.
WB / Human
